My bad play on words aside, Famo.us really is almost famous. I say “almost” because it’s a closed beta and there are several things that might hold it back. It appears that it doesn’t work on any version of IE yet and it’s not clear if that’s in the plans or not. It also gets its performance from making an end-run around a lot of CSS, using matrix3D transforms to GPU-accelerate various operations. The end result is some code that is pretty obtuse looking and not very semantic. You can’t argue with the results though. I’m speaking in broad terms here but you can google for a preso they did late last year that delivers a good overview of what they’re up to. The other big question in my mind is how the more standards-focused folk will feel about this.
I’m curious how this will all play out with Responsive Design and Progressive Enhancement though. It’s still a beta so we’ll have to wait and see.